HYDROCODONE 5 MG/325 MG TABLETS | GOOD QUALITY

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Hydrocodone 5 mg/325 mg Tablets is the powerful main ingredient in narcotic painkillers for moderate to severe pain. It is often administered orally to treat short-term dental and injury-related pain.

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HYDROCODONE 5 MG/325 MG TABLETS

Hydrocodone 5 mg/325 mg Tablets is the powerful main ingredient in narcotic painkillers for moderate to severe pain. It is often administered orally to treat short-term dental and injury-related pain.

People who use hydrocodone over a long period of time or in larger doses may start showing symptoms of hydrocodone addiction.

Hydrocodone is considered an “opioid,” or a semi-synthetic opiate. It’s similar to drugs like morphine, codeine and oxycodone.

Hydrocodone relieves pain by binding pain receptors (opioid receptors) in the central nervous system. This weakens the signal for pain in the brain and can produce feelings of elation. Hydrocodone 5 mg

Hydrocodone is an opioid painkiller used in combination with other ingredients including acetaminophen and ibuprofen. Different ingredient combinations are prescribed for different uses. For example, some hydrocodone combination medications are used for moderate to severe pain relief. Others are used to treat a cough. Any painkiller that contains hydrocodone requires a doctor’s prescription. Hydrocodone 5 mg

Hydrocodone combined with acetaminophen is also known as Vicodin, Lortab, Lorcet, Norco, Anesxia, Co-Gesic, Ceta-Plus, Hydrocet, and Zydone. When combined with ibuprofen, it is known as Vicoprofen.

HOW HYDROCODONE 5 MG/325 MG TABLETS WORKS

Hydrocodone is an opiate analgesic that is always taken in combination with at least one other type of medication. It works by changing the way the central nervous system responds to pain in the body. A hydrocodone combination that is used to treat a cough works by decreasing activity in the part of the brain that causes coughing. Hydrocodone 5 mg

It is available in both short-acting and long-acting, or extended release, forms of pain control. Hydrocodone products come in the forms of tablets, capsules, and syrups. If you are prescribed hydrocodone, it is important that you take your medication exactly as instructed by your doctor. Hydrocodone 5 mg

SIDE EFFECTS OF HYDROCODONE

Like all medications, hydrocodone has side effects. Contact your doctor immediately if any of these symptoms are severe or do not go away:

  • Nausea and/or vomiting
  • Constipation
  • Anxiety and/or mood changes
  • Confusion
  • Dizziness or lightheadedness
  • Difficulty urinating
  • Dry mouth and throat
  • Itching and/or rash

Other side effects are more serious. Seek immediate medical attention if you experience tightness in the chest or slowed or irregular breathing.

  • Slowed or irregular breathing
  • Chest tightness

HOW HYDROCODONE IS USED

Hydrocodone 5 mg/325 mg Tablets is combined with acetaminophen (the active ingredient in Tylenol) or ibuprofen in brand names such as Vicodin, Norco and Lortab. The Food and Drug Administration has also approved a pure hydrocodone product known as Zohydro. Hydrocodone 5 mg 

Those abusing hydrocodone may crush up their pills and snort or inject the contents. In 2014, lawmakers recognized the increasing dangers of abuse and addiction of hydrocodone combination products such as Vicodin and changed them from a Schedule III to Schedule II controlled substance. Hydrocodone 5 mg

HYDROCODONE BRAND NAMES

There are several versions of hydrocodone marketed in the United States. Those with an addiction to hydrocodone likely have a specific brand they prefer. This could be based on many reasons that are both practical and psychological. Hydrocodone 5 mg

Pharmacodynamics

Hydrocodone (and metabolite) at opioid receptors
Compound Affinities (Ki) Ratio Ref
MOR DOR KOR MOR:DOR:KOR
Hydrocodone 11.1 nM 962 nM 501 nM 1:87:45 [44]
Hydromorphone 0.47 nM 18.5 nM 24.9 nM 1:39:53 [45]
Equianalgesic doses[46][47][48]
Compound Route Dose
Codeine PO 200 mg
Hydrocodone PO 20–30 mg
Hydromorphone PO 7.5 mg
Hydromorphone IV 1.5 mg
Morphine PO 30 mg
Morphine IV 10 mg
Oxycodone PO 20 mg
Oxycodone IV 10 mg
Oxymorphone PO 10 mg
Oxymorphone IV 1 mg

Hydrocodone is a highly selective full agonist of the μ-opioid receptor (MOR).[27][49][44] This is the main biological target of the endogenous opioid neuropeptide β-endorphin.[50] Hydrocodone has low affinity for the δ-opioid receptor (DOR) and the κ-opioid receptor (KOR), where it is an agonist similarly.[44]

Studies have shown hydrocodone is stronger than codeine but only one-tenth as potent as morphine at binding to receptors and reported to be only 59% as potent as morphine in analgesic properties. However, in tests conducted on rhesus monkeys, the analgesic potency of hydrocodone was actually higher than morphine.[6] Oral hydrocodone has a mean equivalent daily dosage (MEDD) factor of 0.4, meaning that 1 mg of hydrocodone is equivalent to 0.4 mg of intravenous morphine. However, because of morphine’s low oral bioavailability, there is a 1:1 correspondence between orally administered morphine and orally administered hydrocodone.[51] The relative milligram strength of hydrocodone to codeine is given as 6 fold, that is 5 mg has the effect of 30 mg of codeine; by way of the Roman numeral VI this is said to have given rise to the trade name Vicodin.

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100 tablets, 200 tablets, 300 tablets

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