Avanafil (stendra) | 100% Good Quality

$220.00

STENDRA is a prescription medicine used to treat erectile dysfunction (ED) that can be taken as early as ~15 minutes before sexual activity. Avanafil (stendra).

  • A 100-mg and 200-mg tablet can be taken as early as ~15 minutes before sexual activity
  • STENDRA only works when you are sexually stimulated
  • Do not take STENDRA more than once a day
  • STENDRA is not for use in women or in children under 18 years of age
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Description

What is Avanafil Stendra?

Stendra (avanafil) relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body.

Stendra is used to treat erectile dysfunction (impotence).

Stendra should not be taken by a woman or a child.

Avanafil (stendra) Warnings.

Taking Stendra with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take avanafil if you also take riociguat (Adempas) or a nitrate drug such as nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate. Avanafil (stendra).

If you become dizzy or nauseated during sexual activity, or if you have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect.Avanafil (stendra).

Stop using Stendra and get emergency medical help if you have sudden vision loss. Avanafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking a similar medication called sildenafil (Viagra). Most of these people also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old.Avanafil (stendra).

Do not take this medicine more than once a day. Allow 24 hours to pass between doses. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Before taking this medicine(Avanafil (stendra)

You should not take Stendra if you are allergic to avanafil, or:

Do not take avanafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (“poppers”). Taking avanafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.Avanafil (stendra).

To make sure Stendra is safe for you, tell your doctor if you have ever had:

Stendra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil (Viagra) or other drugs similar to avanafil. Most of these people also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether avanafil is the actual cause of vision loss.Avanafil (stendra).

Stendra is for use only in men. It is not known whether this medicine would be harmful if used by a woman during pregnancy or while breast-feeding.

How should I take Stendra?

Take Stendra exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.Avanafil (stendra).

Stendra can be taken with or without food.

Stendra is usually taken only when needed, about 15 to 30 minutes before sexual activity. Follow your doctor’s instructions.

Stendra can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.

Do not take this medicine more than once a day. Allow 24 hours to pass between doses.

Call your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Store at room temperature away from moisture, heat, and light.

Dosing information

Usual Adult Dose for Erectile Dysfunction:

Initial dose: 100 mg orally as needed approximately 15-30 minutes before sexual activity.
Maintenance dose: 50 to 200 mg orally as needed 15-30 minutes before sexual activity.
Maximum dose: 200 mg orally once a day

Comments:
-The lowest dose that provides benefit should be taken.
-Sexual stimulation is needed for a response to treatment.

Use: Treatment of erectile dysfunction

What happens if I miss a dose?

Since this medicine is used as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What to avoid

Drinking alcohol can increase certain side effects of avanafil. Avoid drinking more than 3 alcoholic beverages while you are taking Stendra.

Grapefruit may interact with avanafil and lead to unwanted side effects. Avoid the use of grapefruit products.

This medication will not protect you from sexually transmitted diseases–including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.

Stendra side effects

Get emergency medical help if you have signs of an allergic reaction to Stendra: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Stendra and get emergency medical help if you have sudden vision loss.

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of Stendra.Avanafil (stendra).

Stop using this medicine and call your doctor at once if you have:

  • vision changes, sudden vision loss;
  • ringing in your ears, or sudden hearing loss;
  • pain, swelling, warmth, or redness in one or both legs;
  • shortness of breath, swelling in your hands or feet;
  • a light-headed feeling, like you might pass out; or
  • penis erection that is painful or lasts 4 hours or longer.

Common Stendra side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Stendra?

Do not take avanafil with similar medicines such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (LevitraStaxyn). These medicines also have other brand names (AdcircaRevatio) that are used to treat a condition called pulmonary arterial hypertension.Avanafil (stendra).

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may interact with avanafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.Avanafil (stendra).

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Stendra only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Stendra vs. Viagra: Differences, similarities, and which is better for you.

If you suffer from erectile dysfunction (ED), you are not alone. An estimated 15 to 30 million men in the United States experience ED. Stendra (avanafil) and Viagra (sildenafil) are two medications used in the treatment of ED. They belong to a group of FDA-approved prescription medications called phosphodiesterase-5 inhibitors (PDE5 inhibitors). Other drugs in this class of ED medications include Cialis (tadalafil) and Levitra (vardenafil).Avanafil (stendra).

PDE5 inhibitors work by increasing both the levels and activity of nitric oxide. By doing this, there is better blood flow to the penis, causing an erection. The medications also help to prolong erections and increase sexual satisfaction. It is important to note that PDE5 inhibitors work in conjunction with sexual stimulation.Avanafil (stendra).

What are the main differences between Stendra and Viagra?

Stendra and Viagra are both PDE5 inhibitors used in the treatment of erectile dysfunction.

Stendra is currently only available in a brand name only. The chemical name is avanafil, but the drug is not yet available as avanafil, only as brand-name Stendra.

Stendra should be taken as a 100 mg or 200 mg dose, as early as 15 minutes prior to sexual activity. It can also be dosed at 50 mg approximately 30 minutes before sexual activity.

Viagra should be taken approximately one hour prior to sexual activity. Whether you take Stendra or Viagra, only one dose should be taken in one day.

Regardless of the drug or dose, the medication should be accompanied by sexual stimulation in order to be effective. Either drug may be taken with or without food.

Main differences between Stendra and Viagra
Stendra Viagra
Drug class PDE5 inhibitor PDE5 inhibitor
Brand/generic status Brand Brand and generic
What is the generic name? Avanafil (but it is not yet available in generic) Sildenafil
What form does the drug come in? Tablet (50 mg, 100 mg, 200 mg) Tablet (25 mg, 50 mg, 100 mg)
What is the standard dosage? Example: one 100 mg tablet 15 minutes before sexual activity
OR
one 50 mg tablet approximately 30 minutes before sexual activity
*not to be taken more than once in a day
Example: one 50 mg tablet one hour prior to sexual activity but can range anywhere from 25 mg to 100 mg taken 30 minutes to 4 hours before sexual activity
*not to be taken more than once in a day
How long is the typical treatment? As needed As needed
Who typically uses the medication? Adult males Adult males

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Conditions treated by Stendra and Viagra

Both Stendra and Viagra (What is Viagra?) have only one official indication—the treatment of ED in men.  However, both drugs may be used off-label for Raynaud’s phenomenon. Viagra is sometimes used off-label to treat female sexual arousal disorder.Avanafil (stendra).

Condition Stendra Viagra
Erectile dysfunction Yes Yes
Raynaud’s phenomenon Off-label Off-label
Female sexual arousal disorder No Off-label
Treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worsening No Yes, but not as Viagra. Only when prescribed as Revatio (or its generic sildenafil), in doses of 20 mg three times daily

Is Stendra or Viagra more effective?

review of clinical studies concluded that Stendra was comparable in efficacy to Viagra, as well as other PDE5 inhibitors. The study also noted that Stendra is more favorable in terms of side effects and drug interactions, and has less of an effect on lowering blood pressure.Avanafil (stendra).

Another review of studies concluded that Stendra is safe and effective, but speculated an uncertainty for Stendra’s place in the market. This is because all PDE5 inhibitors are similar, and besides Stendra, all of them are available in generic, offering a significant money-saving advantage to the patient. The authors predicted that, “a new agent without such a long history may have difficulty finding a market share.”Avanafil (stendra).

The most effective medication for you should only be determined by your doctor, who can look at your medical condition(s), history, and other medications you take.

Coverage and cost comparison of Stendra vs. Viagra

There is a wide variation in regards to insurance coverage for Stendra or Viagra. Some insurance companies pay for them, and others do not. Some insurances have a limit on the quantity that you can fill, for example, your insurance may allow four tablets per month on an ED medication.Avanafil (stendra).

A standard prescription of #10 tablets of Stendra 100 mg (available in brand-name only) will cost about $680 with a SingleCare discount card.

A standard prescription of #10 tablets of sildenafil 50 mg (generic Viagra) tablets can range from $150-$300 depending on which pharmacy you use.

Stendra Viagra
Typically covered by insurance? Coverage varies Coverage varies
Typically covered by Medicare Part D? No No
Standard dosage #10 tablets, 100 mg #10 tablets, 50 mg
Typical Medicare copay Varies (patients often pay out of pocket) Varies (patients often pay out of pocket)
SingleCare cost $680 $150+

Get the SingleCare prescription discount card

Common side effects of Stendra vs. Viagra

Stendra and Viagra have many similar side effects, however, it is important to note that the frequency varies by dose. For example, 16% of patients taking Viagra 25 mg experienced headaches, but with a dose of 100 mg, 28% of patients experienced headaches.Avanafil (stendra).

With Stendra, the most common side effects are headache, flushing, nasal congestion, and back pain. The most common side effects of Viagra are headache, flushing, nasal congestion, and indigestion.Avanafil (stendra).

This is not a complete list of side effects. Consult your healthcare provider for a full list.

Stendra Viagra
   Side Effect Applicable? Frequency Applicable? Frequency
   Headache Yes 5.1-10.5% Yes 16-28%
   Flushing Yes 3.2-4.3% Yes 10-19%
   Nasal congestion Yes 1.8-2.9% Yes 4-9%
   Back pain Yes 1.1-3.2% Yes 3-4%
   Indigestion Yes 1-2% Yes 3-17%
   Dizziness Yes 1-2% Yes 3-4%
   Nausea Yes 1-2% Yes 2-3%

Source: DailyMed (Stendra), DailyMed (Viagra)

Drug interactions of Stendra and Viagra

Patients taking Stendra or Viagra should never take nitrate medications, such as nitroglycerin. The combination is contraindicated (should never be used together) because it could result in dangerously low blood pressure.Avanafil (stendra).

There are many drugs that, in combination with Stendra or Viagra, could cause blood pressure to decrease. These include alpha blockers (such as alfuzosin, terazosin, or tamsulosin), riociguat (a drug used to treat pulmonary arterial hypertension), and blood pressure medications. These drugs should only be used with Stendra or Viagra with caution, and with appropriate monitoring by your healthcare provider.Avanafil (stendra).

Drugs are metabolized with the help of enzymes, and a common one is the cytochrome P450 3A4 (CYP3A4) system. A drug that inhibits CYP3A4 can cause another drug to build up in the system, by inhibiting, or slowing down, how the other drug is processed. For example, if drug A inhibits drug B, you will get a buildup of drug B in your body, which could lead to increased side effects. Drugs can be strong inhibitors or moderate inhibitors.Avanafil (stendra).

Patients taking a strong 3A4 inhibitor should not take Stendra, and patients taking a moderate inhibitor should take no more than 50 mg, and only if approved by the doctor. Viagra should be started at the lowest dose of 25 mg when given with a strong 3A4 inhibitor. If taken with the protease inhibitor ritonavir, Viagra should be taken as 25 mg at least 48 hours apart.Avanafil (stendra).

Other drug interactions may occur; consult your healthcare professional for a full list of drug interactions.

Drug Drug Class Stendra Viagra
Nitroglycerin Nitrates Yes Yes
Riociguat Guanylate cyclase stimulator Yes Yes
Alfuzosin
Tamsulosin
Terazosin
Alpha blockers Yes Yes
Lisinopril
Amlodipine
Bystolic
Metoprolol
Losartan
Ramipril
etc.
Antihypertensives Yes Yes
Ketoconazole
Itraconazole, Clarithromycin
Ritonavir
Saquinavir
Nelfinavir
Indinavir
Atazanavir
Strong CYP 3A4 inhibitors Yes Yes
Erythromycin
Aprepitant
Diltiazem
Fluconazole
Fosamprenavir
Verapamil
Moderate CYP 3A4 inhibitors Yes Yes

Warnings of Stendra and Viagra

  • Cardiovascular health should be assessed before you take Stendra or Viagra. Certain patients may not be a candidate for Stendra or Viagra. Ask your doctor before taking Stendra or Viagra, if you have any problems with your heart or blood pressure.Avanafil (stendra).
  • Currently, it is recommended that Stendra or Viagra is not used in patients with recent cardiac events, such as a heart attack or stroke, patients with resting low blood pressure (less than 90/50 mmHg) or high blood pressure (more than 170/100 mmHg), and patients with unstable angina. Consult your doctor if you have heart or blood pressure problems.Avanafil (stendra).
  • Stendra or Viagra should not be used in patients who take nitrates such as nitroglycerin, or a guanylate cyclase stimulator such as riociguat, due to increased effects on lowering the blood pressure. Other medications in combination with Stendra or Viagra can affect blood pressure as well (see drug interaction chart).
  • Use Stendra or Viagra with caution in patients with anatomical deformation of the penis.Avanafil (stendra).
  • Occasionally, a prolonged erection (more than 4 hours), or priapism (a painful erection lasting longer than 6 hours) may occur. If an erection lasts longer than 4 hours, seek immediate medical attention. Failure to treat this condition immediately could result in permanent damage.Avanafil (stendra).
  • If you experience a sudden loss of vision or a sudden loss of hearing (which may be accompanied by dizziness or ringing in the ears), stop Stendra or Viagra and seek immediate medical attention.Avanafil (stendra).
  • Avoid substantial amounts of alcohol with Stendra or Viagra, because the combination could lead to an increased heart rate, lower blood pressure, dizziness, and headache.
  • Stendra or Viagra do not protect against sexually transmitted diseases, so other protective measures, such as condoms, should be used.
  • Because Stendra and Viagra are not indicated for women, there is no clinical data about the safety of these drugs in pregnancy. Therefore, it is not recommended to use Stendra or Viagra in pregnancy.Avanafil (stendra).

Frequently asked questions about Stendra vs. Viagra

What is Stendra?

Stendra (avanafil) is a PDE5 inhibitor that treats erectile dysfunction in men. Along with sexual stimulation, it helps increase blood flow to the penis, helping the patient achieve and maintain an erection. Currently, it is only available in brand name; there is no generic available yet.Avanafil (stendra).

What is Viagra?

Viagra (sildenafil) is a PDE5 inhibitor used to treat erectile dysfunction in men. It increases blood flow to the penis (in conjunction with sexual stimulation) so you can achieve and maintain an erection. Viagra is available in brand and generic.Avanafil (stendra).

You may have heard of a drug called Revatio used for ED, instead of Viagra. Revatio is another drug that contains sildenafil, the same ingredient in Viagra. Revatio is used to treat pulmonary arterial hypertension (PAH). Although Revatio is indicated only for PAH, it is often prescribed off-label for ED. Sometimes, when an insurance company does not cover Viagra, a doctor may prescribe Revatio instead, which is usually covered by insurance.Avanafil (stendra).

Are Stendra and Viagra the same?

Not exactly. They are very similar and are in the same category of drugs—PDE5 inhibitors. However, they do have some differences, outlined above.

Is Stendra or Viagra better? / Is Stendra more effective than Viagra?

Looking at trials, both drugs are very similar in efficacy, and both drugs are well-tolerated. One study noted that Stendra may have difficulty finding a place in the market due to its availability only as brand-name, with a much higher price than other PDE5 inhibitors. Viagra seems to be much more popular, but likely due to its lower price and time on the market.  It may sometimes take trial and error to find the medication that is best for you, and your doctor can help you decide.Avanafil (stendra).

Can I use Stendra or Viagra while pregnant?

Because neither drug is indicated for use in women, there are no studies to determine safety in pregnancy. Therefore, it is not recommended to use Stendra or Viagra while pregnant.

Can I use Stendra or Viagra with alcohol?

Alcohol can interfere with the body’s ability to achieve an erection; however, it might be okay in small quantities. Ask your medical provider for advice.Avanafil (stendra).

How long does Stendra last for?

Stendra begins to work as soon as 15-30 minutes after the medication is taken, and can last for up to six hours.Avanafil (stendra).

Is there a generic for Stendra?

Currently, there is no generic for Stendra. When there is a generic available, it will be called by its chemical name, avanafil.Avanafil (stendra).

Can you buy Stendra over the counter?

No. Stendra is only available by prescription in the United States. Viagra is also only available by prescription in the US.Avanafil (stendra).

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